Materials derived from the human elastin-like polypeptide fusion with an antimicrobial peptide strongly promote cell adhesion-Reference-Cited by-同舟云学术

Materials derived from the human elastin-like polypeptide fusion with an antimicrobial peptide strongly promote cell adhesion

Published:2024 Issue: Volume: Page:
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Colomina-Alfaro Laura¹^ORCID,Sist Paola¹^ORCID,D’Andrea Paola¹^ORCID,Urbani Ranieri²^ORCID,Marchesan Silvia²^ORCID,Stamboulis Artemis³^ORCID,Bandiera Antonella¹^ORCID

Affiliation:

1. Department of Life Sciences, University of Trieste, 34127 Trieste, Italy

2. Department of Chemical and Pharmaceutical Sciences, University of Trieste, 34127 Trieste, Italy

3. School of Metallurgy and Materials, Biomaterials Research Group, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK

Abstract

An elastin-like fusion of the difficult-to-synthesise human β-defensin 1 domain was produced retaining the antimicrobial properties of the peptide. The new biopolymer was used to produce coatings and hydrogel-like matrices that promoted cell adhesion.

Funder

H2020 Health

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D4TB00319E

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