Novel semiconducting nano-agents incorporating tirapazamine for imaging guided synergistic cancer hypoxia activated photo-chemotherapy

Author:

Zhang Guorong12345ORCID,Wang Weixiang67234,Zou Huihui87234ORCID,Wei Zheng97234,Song Chuanhui87234ORCID,Ran Jianchuan87234,Cao Zichen87234,Cai Yu101112134,Han Wei87234

Affiliation:

1. Department of Orthodontics, Nanjing Stomatological Hospital

2. Medical School of Nanjing University

3. Nanjing

4. China

5. Central Laboratory of Stomatology

6. Fourth Clinical Division

7. Nanjing Stomatological Hospital

8. Department of Oral and Maxillofacial Surgery

9. Pediatric Dentistry

10. Clinical Research Institute

11. Zhejiang Provincial People's Hospital

12. People's Hospital of Hangzhou Medical College

13. Hangzhou 310014

Abstract

The imaging guided synergistic photothermal, photodynamic and chemical therapy of ITTC NPs and TPZ have great potential for clinical transformation in tumor diagnosis and therapy.

Funder

Natural Science Foundation of Jiangsu Province

Jiangsu Provincial Medical Youth Talent

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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