Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors

Author:

Hettiarachchi Sajini D.1234ORCID,Graham Regina M.56274ORCID,Mintz Keenan J.1234ORCID,Zhou Yiqun1234ORCID,Vanni Steven56274,Peng Zhilli1234,Leblanc Roger M.1234ORCID

Affiliation:

1. Department of Chemistry

2. University of Miami

3. Coral Gables

4. USA

5. Department of Neurological Surgery

6. Miller School of Medicine

7. Miami

Abstract

Most of the dual nano drug delivery systems fail to enter malignant brain tumors due to a lack of proper targeting systems and the size increase of the nanoparticles after drug conjugation. Therefore, a triple conjugated system was developed with carbon dots (C-dots) which has an average particle size of 1.5–1.7 nm.

Funder

National Institutes of Health

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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