Synthesis and biological evaluation of a new class of multi-target heterocycle piperazine derivatives as potential antipsychotics-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of a new class of multi-target heterocycle piperazine derivatives as potential antipsychotics

Published:2021 Issue:28 Volume:11 Page:16931-16941
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Gao Lanchang¹²³⁴⁵,Hao Chao⁶⁷⁸⁹¹⁰,Ma Ru¹²³⁴⁵,Chen Jiali⁶⁷⁸⁹¹⁰,Zhang Guisen¹²³⁴⁵,Chen Yin¹²³⁴⁵^ORCID

Affiliation:

1. Jiangsu Key Laboratory of Marine Biological Resources and Environment

2. Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening

3. School of Pharmacy

4. Jiangsu Ocean University

5. Lianyungang 222005

6. Department of Biomedical Engineering

7. College of Life Science and Technology

8. Huazhong University of Science and Technology

9. Wuhan 430074

10. China

Abstract

In this study, we designed and synthesized a novel series of multi-receptor ligands as polypharmacological antipsychotic agents by using a multi-receptor affinity strategy.

Funder

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA02426D

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