Counteracting the inhibitory effect of proteins towards lung surfactant substitutes: a fluorocarbon gas helps displace albumin at the air/water interface

Author:

Nguyen Phuc Nghia1234,Veschgini Mariam5678,Tanaka Motomu5678,Waton Gilles1234,Vandamme Thierry91011,Krafft Marie Pierre1234

Affiliation:

1. Systèmes Organisés Fluorés à Finalités Thérapeutiques (SOFFT)

2. Institut Charles Sadron (ICS) CNRS

3. Université de Strasbourg (UPR 22)

4. 67034 Strasbourg Cedex 2, France

5. Physical Chemistry of Biosystems

6. Institute of Physical Chemistry

7. University of Heidelberg

8. 69120 Heidelberg, Germany

9. Laboratoire de Conception et Application de Molécules Bioactives (CNRS UMR 7199)

10. Université de Strasbourg

11. 67401 Illkirch Cedex, France

Abstract

Perfluorohexane accelerates the displacement of albumin by dipalmitoylphosphatidylcholine at an interface submitted to sustained sinusoidal oscillations.

Funder

Agence Nationale de la Recherche

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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