A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A-Reference-Cited by-同舟云学术

A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A

Published:2022 Issue:22 Volume:147 Page:5082-5090
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Zhang Fengqiu¹²,Shao Changsheng²³,Wu Yahui²³,Zhao Wei¹,Jing Xumiao¹,Fang Cao²³,Huang Qing²³^ORCID

Affiliation:

1. Henan Key Laboratory of Ion-beam Bioengineering, School of Physics and Microelectronics, Zhengzhou University, Zhengzhou, China

2. CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Institute of Intelligent Machines, Hefei Institutes of Physical Sciences, Chinese Academy of Sciences, Hefei, China

3. Science Island Branch of Graduate School, University of Science &Technology of China, Hefei, China

Abstract

The glycolysis suppression process due to treatment by trichostatin A (TSA), a typical histone deacetylase (HDAC) inhibitor, could be observed in situ using the GFP fluorescent probe in the cell which is sensitive to intracellular pH (pHi) change.

Funder

National Natural Science Foundation of China

Hefei Institutes of Physical Science, Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D2AN01114J

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