Identification of potent anticancer copper(ii) complexes containing tripodal bis[2-ethyl-di(3,5-dialkyl-1H-pyrazol-1-yl)]amine moiety-Reference-Cited by-同舟云学术

Identification of potent anticancer copper(ii) complexes containing tripodal bis[2-ethyl-di(3,5-dialkyl-1H-pyrazol-1-yl)]amine moiety

Published:2021 Issue:33 Volume:50 Page:11521-11534
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Massoud Salah S.¹²^ORCID,Louka Febee R.¹,Dial Madison T.¹,Malek Andrew J.¹,Fischer Roland C.³^ORCID,Mautner Franz A.⁴,Vančo Ján⁵,Malina Tomáš⁵,Dvořák Zdeněk⁶,Trávníček Zdeněk⁵^ORCID

Affiliation:

1. Department of Chemistry, University of Louisiana at Lafayette, P.O. Box 43700, Lafayette, LA 70504, USA

2. Department of Chemistry, Faculty of Science, Alexandria University, Moharam Bey 21511, Alexandria, Egypt

3. Institut für Anorganische Chemische, Technische Universität Graz, Stremayrgasse 9/V, A-8010 Graz, Austria

4. Institut für Physikalische and Theoretische Chemie, Technische Universität Graz, Stremayrgasse 9/II, A-8010, Graz, Austria

5. Czech Advanced Technology and Research Institute, Regional Centre of Advanced Technologies and Materials, Palacký University, Křížkovského 511/8, CZ-779 00 Olomouc, Czech Republic

6. Department of Cell Biology and Genetics, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic

Abstract

Five Cu(ii) complexes with tripodal pyrazolyl-amines have been synthesized and structurally characterized. Three of the complexes revealed significantly higher in vitro cytotoxicity than cisplatin against five human cancer cell lines.

Funder

University of Louisiana at Lafayette

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT01724A

Reference66 articles.

1. https://www.breitbart.com/politics/2018/02/21/revealed-top-10-leading-causes-of-death-in-usa/

2. https://www.healthline.com/health/leading-causes-of-death#worldwide-causes