Formation of compound I in heme bound Aβ-peptides relevant to Alzheimer's disease-Reference-Cited by-同舟云学术

Formation of compound I in heme bound Aβ-peptides relevant to Alzheimer's disease

Published:2019 Issue:36 Volume:10 Page:8405-8410
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Pal Ishita¹²³,Nath Arnab Kumar¹²³,Roy Madhuparna¹²³,Seal Manas¹²³,Ghosh Chandradeep¹²³,Dey Abhishek¹²³^ORCID,Dey Somdatta Ghosh¹²³^ORCID

Affiliation:

1. Indian Association for the Cultivation of Science

2. Kolkata 700032

3. India

Abstract

Compound I is an active oxidant responsible for the peroxidase activity of heme–Aβ and can cause oxidative degradation of neurotransmitters like serotonin, a marker of Alzheimer's disease.

Funder

Department of Science and Technology, Ministry of Science and Technology

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC01679A

Reference61 articles.

1. On the early diagnosis of Alzheimer's Disease from multimodal signals: A survey

2. 3D structure of Alzheimer's amyloid- (1-42) fibrils

3. Amyloid Precursor Protein Processing and Alzheimer's Disease

4. The amyloid precursor protein of Alzheimer’s disease and the Aβ peptide

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