Radiosynthesis and evaluation of acetamidobenzoxazolone based radioligand [11C]N′-MPB for visualization of 18 kDa TSPO in brain-Reference-Cited by-同舟云学术

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Radiosynthesis and evaluation of acetamidobenzoxazolone based radioligand [11C]N′-MPB for visualization of 18 kDa TSPO in brain

Published:2020 Issue:19 Volume:44 Page:7912-7922
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Tiwari Anjani Kumar¹²³⁴⁵^ORCID,Zhang Yiding¹²³⁴⁵,Yamasaki Tomoteru¹²³⁴⁵,Kumari Neelam⁶⁷⁸⁹,Fujinaga Masayuki¹²³⁴⁵,Mori Wakana¹²³⁴⁵,Hatori Akiko¹²³⁴⁵,Nengaki Nobuki¹²³⁴⁵,Mishra Anil Kumar⁶⁷⁸⁹,Zhang Hong¹⁰¹¹¹²¹³,Zhang Ming-Rong¹²³⁴⁵^ORCID

Affiliation:

1. Department of Radiopharmaceutics Development

2. National Institute of Radiological Sciences

3. National Institutes for Quantum and Radiological Science and Technology

4. Chiba 263-8555

5. Japan

6. Division of Cyclotron and Radiopharmaceutical Sciences

7. Institute of Nuclear Medicine and Allied Sciences

8. Delhi 110054

9. India

10. Department of Nuclear Medicine and Medical PET Center

11. The Second Hospital of Zhejiang University School of Medicine

12. Hangzhou 310009

13. China

Abstract

Modified acetamidobenzoxazolone radioligand [11C]N′-MPB for visualization of 18 kDa TSPO.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ00509F

Reference29 articles.

1. Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

2. Radiolabelled Molecules for Imaging the Translocator Protein (18 kDa) Using Positron Emission Tomography

3. Translocator protein 18 kDa (TSPO): Molecular sensor of brain injury and repair

4. Synthesis of N-(11C) methyl, N-(methyl-1 propyl), (chloro-2 phenyl)-1 isoquinoleine carboxamide-3 (PK 11195): A new ligand for peripheral benzodiazepine receptors

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