Advanced nanomaterials for modulating Alzheimer's related amyloid aggregation

Author:

Shao Xu1ORCID,Yan Chaoren2ORCID,Wang Chao1,Wang Chaoli3,Cao Yue4,Zhou Yang5,Guan Ping1,Hu Xiaoling1,Zhu Wenlei4ORCID,Ding Shichao6ORCID

Affiliation:

1. Department of Chemistry, School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, 127 Youyi Road, Xi'an 710072, China

2. School of Medicine, Xizang Minzu University, Key Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Disease of Tibet Autonomous Region, Xianyang, Shaanxi 712082, China

3. Department of Pharmaceutical Chemistry and Analysis, School of Pharmacy, Air Force Medical University, 169 Changle West Road, Xi'an 710032, China

4. School of the Environment, School of Chemistry and Chemical Engineering, State Key Laboratory of Analytical Chemistry for Life Science, State Key Laboratory of Pollution Control & Resource Reuse, Nanjing University, Nanjing, 210023, P. R. China

5. Key Laboratory for Organic Electronics & Information Displays (KLOEID), Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications (NJUPT), Nanjing 210046, China

6. School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA

Abstract

Based on the dimensional scale, this review summaries the use of nanomaterials in the modulation of amyloid aggregation. The effects include intermolecular interaction, chelation, photothermal effect, photocatalytic oxidation, and drug delivery.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shaanxi Province

Shaanxi Provincial Science and Technology Department

Northwestern Polytechnical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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