Anti-proliferative effects of diterpenoids from Sagittaria trifolia L. tubers on colon cancer cells by targeting the NF-κB pathway-Reference-Cited by-同舟云学术

Anti-proliferative effects of diterpenoids from Sagittaria trifolia L. tubers on colon cancer cells by targeting the NF-κB pathway

Published:2020 Issue:9 Volume:11 Page:7717-7726
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Assani Israa¹²³⁴⁵^ORCID,Du Ying¹²³⁴⁵,Wang Chun-Gu¹²³⁴⁵,Chen Lei¹²³⁴⁵,Hou Pei-Lei¹²³⁴⁵,Zhao Shi-Feng¹²³⁴⁵,Feng Yan¹²³⁴⁵,Liu Ling-Fei¹²³⁴⁵,Sun Bo¹²³⁴⁵,Li Yan¹²³⁴⁵,Liao Zhi-Xin¹²³⁴⁵^ORCID,Huang Ri-Zhen⁶⁷⁸⁹

Affiliation:

1. Department of Pharmaceutical Engineering

2. School of Chemistry and Chemical Engineering

3. Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research

4. Southeast University

5. Nanjing 211189

6. College of Biotechnology

7. Guilin Medical University

8. Guilin 541100

9. China

Abstract

A novel and ten known diterpenoids were isolated from the ethanolic crude extract of the fresh tubers of Sagittaria trifolia L. Compound 11 exhibited strong inhibitory activity on Hct-116 cancer cells by blocking the NF-κB signaling pathway.

Funder

National Natural Science Foundation of China

QingHai Department of Science and Technology

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO00228C

Reference51 articles.

1. Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer