Tertiary amines as a C1 synthon: metal-free synthesis of quinolines and 2-substituted quinolines<i>via</i>[3+2+1] aerobic cyclization and C

Tertiary amines as a C1 synthon: metal-free synthesis of quinolines and 2-substituted quinolinesvia[3+2+1] aerobic cyclization and C–N bond cleavage

Published:2023 Issue:11 Volume:47 Page:5155-5159
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Liu Jing-Yuan¹,Wang Zhen-Ying¹,Li Qiang¹^ORCID,Li Dacheng¹,Dou Jianmin¹

Affiliation:

1. Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology, School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252000, P. R. China

Abstract

An I2-mediated aerobic cyclization reaction of anilines, alkynes, and tertiary amine has been reported. In this protocol, a novel strategy for the synthesis of quinolines using tertiary amines as a C1 synthonviaC–N bond cleavage.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D2NJ04119G

Reference48 articles.

1. Transition-Metal-Catalyzed Cleavage of C–N Single Bonds

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3. No Making Without Breaking: Nitrogen-Centered Carbonylation Reactions