Characterization of a conglomerate-forming derivative of (±)-milnacipran and its enantiomeric resolution by preferential crystallization-Reference-Cited by-同舟云学术

Characterization of a conglomerate-forming derivative of (±)-milnacipran and its enantiomeric resolution by preferential crystallization

Published:2016 Issue:55 Volume:6 Page:49876-49882
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sanfilippo Claudia¹²³,Forni Alessandra⁴⁵³,Patti Angela¹²³

Affiliation:

1. CNR – Istituto di Chimica Biomolecolare

2. I-95126 Catania

3. Italy

4. CNR – Istituto di Scienze e Tecnologie Molecolari del CNR

5. I-20133 Milano

Abstract

The conglomerate nature of crystals of an N-isobutyramide derivative of milnacipran was efficiently exploited for its enantiomeric resolution by preferential crystallization.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA07745E

Reference39 articles.

1. Molecular Chirality in Chemistry and Biology: Historical Milestones

2. Homochiral Drugs: A Demanding Tendency of the Pharmaceutical Industry

3. Industrial Methods for the Production of Optically Active Intermediates

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