Molecular basis for resistance against phosphonate antibiotics and herbicides
Author:
Affiliation:
1. Department of Biochemistry
2. USA
3. Institute for Genomic Biology
4. University of Illinois at Urbana Champaign
5. Center for Biophysics and Computational Biology
Abstract
Research studies in recent years have illuminated data on the mechanisms and targets of phosphonic acid antibiotics and herbicides, including fosfomycin, glyphosate, fosmidomycin and FR900098.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/MD/C5MD00351B
Reference77 articles.
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4. Detection and Characterization of a Phospholactoyl-Enzyme Adduct in the Reaction Catalyzed by UDP-N-acetylglucosamine Enolpyruvoyl Transferase, MurZ
5. Evidence That the Fosfomycin Target Cys115 in UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA) Is Essential for Product Release
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