Trastuzumab-decorated nanoparticles for in vitro and in vivo tumor-targeting hyperthermia of HER2+ breast cancer

Author:

Hamzehalipour Almaki Javad12345ORCID,Nasiri Rozita12345ORCID,Idris Ani12345ORCID,Nasiri Mahtab678910ORCID,Abdul Majid Fadzilah Adibah1112135ORCID,Losic Dusan14151617ORCID

Affiliation:

1. Department of Bioprocess Engineering

2. Faculty of Chemical Engineering c/o Institute of Bioproduct Development

3. Universiti Teknologi Malaysia

4. Johor Bahru

5. Malaysia

6. Advanced Materials Research Centre

7. Department of Materials Engineering

8. Islamic Azad University

9. Najafabad

10. Iran

11. Institute of Marine Biotechnology

12. Universiti Malaysia Terengganu

13. Kuala Terengganu

14. School of Chemical Engineering

15. The University of Adelaide

16. Adelaide

17. Australia

Abstract

In this study, a magnetic core–shell modified tumor-targeting nanocarrier (MNPs-PEG–TRA) was engineered and demonstrated for the efficientin vitroandin vivohyperthermia treatment of breast cancer.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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