Selective desaturation of amides: a direct approach to enamides-Reference-Cited by-同舟云学术

Selective desaturation of amides: a direct approach to enamides

Published:2022 Issue:31 Volume:13 Page:9056-9061
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Li Xinwei¹,Cheng Zengrui¹,Liu Jianzhong¹,Zhang Ziyao¹,Song Song¹^ORCID,Jiao Ning¹²^ORCID

Affiliation:

1. State Key Laboratory of Natural and Biomimetic Drugs, Chemical Biology Center, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. 38, Beijing 100191, China

2. Shanghai Key Laboratory of Green Chemistry and Chemical Processes, East China Normal University, Shanghai 200062, China

Abstract

A novel and regioselective N-α,β-desaturation and dehydrogenative N-β-halogenation of amides was developed. This chemistry with high selectivity and broad substrate scope provides an efficient approach to enamides from simple amides.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Beijing Nova Program

Tencent

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC02210A

Reference113 articles.