Chondrocyte secretome enriched microparticles encapsulated with the chondrocyte membrane to facilitate the chondrogenesis of BMSCs and reduce hypertrophy-Reference-Cited by-同舟云学术

Chondrocyte secretome enriched microparticles encapsulated with the chondrocyte membrane to facilitate the chondrogenesis of BMSCs and reduce hypertrophy

Published:2021 Issue:48 Volume:9 Page:9989-10002
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Tang Zizhao¹²,Lu Yan¹²,Zhang Shixin¹²,Wang Jing³,Wang Qiguang¹²^ORCID,Xiao Yumei¹²^ORCID,Zhang Xingdong¹²

Affiliation:

1. National Engineering Research Center for Biomaterials, Sichuan University, 29 Wangjiang Road, Chengdu, Sichuan, 610065, China

2. College of Biomedical Engineering, Sichuan University, 29 Wangjiang Road, Chengdu, Sichuan, 610065, China

3. College of Materials and Chemistry & Chemical Engineering, Chengdu University of Technology, Chengdu, Sichuan, 610059, China

Abstract

The “artificial chondrocytes” that consist of chondrocyte secretome enriched PLGA microparticles with the encapsulation of chondrocytes’ membrane fragments had facilitated chondrogenesis and reduced hypertrophy of BMSCs in vitro and in vivo.

Funder

National Natural Science Foundation of China

Higher Education Discipline Innovation Project

National Key Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB02319E

Reference40 articles.

1. Potential of silk fibroin/chondrocyte constructs of muga silkworm Antheraea assamensis for cartilage tissue engineering