A synthetic approach towards drug modification: 2-hydroxy-1-naphthaldehyde based imine-zwitterion preparation, single-crystal study, Hirshfeld surface analysis, and computational investigation-Reference-Cited by-同舟云学术

A synthetic approach towards drug modification: 2-hydroxy-1-naphthaldehyde based imine-zwitterion preparation, single-crystal study, Hirshfeld surface analysis, and computational investigation

Published:2024 Issue:10 Volume:14 Page:6476-6493
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Malik Abida Naseem¹,Ali Akbar²^ORCID,Ashfaq Muhammad¹,Tahir Muhammad Nawaz¹,Alam Mohammad Mahtab³,Mostafa Mohamed S.⁴^ORCID,Kuznetsov Aleksey⁵

Affiliation:

1. Department of Physics, University of Sargodha, Sargodha 40100, Pakistan

2. Department of Chemistry, Government College University Faisalabad, 38000-Faisalabad, Pakistan

3. Department of Basic Medical Sciences, College of Applied Medical Science, King Khalid University, Abha 61421, Saudi Arabia

4. Department of Physical Sciences, College of Science, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia

5. Departamento de Química, Campus Santiago Vitacura, Universidad Tecnica Federico Santa María, Av. Santa María 6400 Vitacura, 7660251, Chile

Abstract

This work is about the modification of pyrimethamine and 4-amino-N-(2,3-dihydrothiazol-2-yl)benzenesulfonamide via condensation reaction with 2-hydroxy-1-naphthaldehyde to produce new organic zwitterionic compounds DSPIN and ACPIN in methanol.

Funder

King Khalid University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA08727A

Reference75 articles.

1. The Era of Biomedicine: Science, Medicine, and Public Health in Britain and France after the Second World War

2. Antibiotics versus no treatment for toxoplasma retinochoroiditis

3. Hydrogen-bonded supramolecular ribbons in the antifolate drug pyrimethamine

4. Intercontinental Spread of Pyrimethamine-Resistant Malaria

5. Evolution of Resistance to Sulfadoxine-Pyrimethamine in Plasmodium falciparum

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Single crystal XRD, Hirshfeld surface analysis and computational approach for exploration of novel xanthene derivative;Journal of Molecular Structure;2025-02

2. Exploring the coordination polymeric behavior of cobalt based on sulfamethizole: Crystal structure, Hirshfeld surface analysis, DFT calculations and biological activities;Journal of Molecular Structure;2024-12

3. Synthesis, spectral elucidation and DNA binding studies of cadmium(II) carboxylates with nitrogen donor heteroligands;Inorganic Chemistry Communications;2024-10

4. Pyrazolyl-derived zinc(II) and cadmium(II) complexes: Synthesis, spectral characterization, single crystal insights, Hirshfeld surface analysis, and in silico DNA interaction studies;Inorganic Chemistry Communications;2024-10

5. Supramolecular assemblies of Zn(II) complex based on dithiolate-amine binary ligands: Synthesis, crystal structure, Hirshfeld surface, DFT, molecular docking, and anticancer studies;Inorganic Chemistry Communications;2024-09