The isolation and analysis of fetal nucleated red blood cells using multifunctional microbeads with a nanostructured coating toward early noninvasive prenatal diagnostics

Author:

Zhang Qilin12345,Zhang Kelin12345,Guo Yuping6785,Wei Xiaoyun910115,Sun Yue12345,Cai Bo121314158,Shi Yunfan12345,Du Yunxiao12345,Liu Yuling6785,Fan Cuifang6785,Zhao Xing-Zhong12345ORCID

Affiliation:

1. Key Laboratory of Artificial Micro- and Nano-Structures of Ministry of Education

2. School of Physics and Technology

3. Wuhan University

4. Wuhan 430072

5. China

6. Department of Obstetrics and Gynecology

7. Renmin Hospital of Wuhan University

8. Wuhan

9. Key Laboratory of Medical Information and 3D Bioprinting of Zhejiang Province

10. Hangzhou Dianzi University

11. Hangzhou 310018

12. Research Center for Tissue Engineering and Regenerative Medicine

13. Union Hospital

14. Tongji Medical College

15. Huazhong University of Science and Technology

Abstract

An innovative platform is demonstrated based on multifunctional microbeads with a nanostructured coating for fNRBC isolation and release.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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