The design, synthesis and evaluation of selenium-containing 4-anilinoquinazoline hybrids as anticancer agents and a study of their mechanism-Reference-Cited by-同舟云学术

The design, synthesis and evaluation of selenium-containing 4-anilinoquinazoline hybrids as anticancer agents and a study of their mechanism

Published:2018 Issue:25 Volume:16 Page:4701-4714
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

An Baijiao¹²³⁴,Zhang Shun¹²³⁴,Hu Jinhui¹²³⁴,Pan Tingting¹²³⁴,Huang Ling¹²³⁴^ORCID,Tang Johnny Cheuk-on⁵⁶⁷⁸,Li Xingshu¹²³⁴^ORCID,Chan Albert S. C.¹²³⁴

Affiliation:

1. School of Pharmaceutical Sciences

2. Sun Yat-sen University

3. Guangzhou 510006

4. China

5. State Key Laboratory of Chirosciences

6. Department of Applied Biology and Chemical Technology

7. The Hong Kong Polytechnic University

8. P.R. China

Abstract

We report the design, synthesis and evaluation of 2-chloro-N-methyl-N-(4-selenocyanatophenyl)quinazolin-4-amine and its analogues as anticancer agents and the mechanism study.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00875B

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