1,6-Conjugated addition-mediated [4 + 1] annulation: an approach to 2,3-dihydrobenzofurans-Reference-Cited by-同舟云学术

1,6-Conjugated addition-mediated [4 + 1] annulation: an approach to 2,3-dihydrobenzofurans

Published:2018 Issue:4 Volume:5 Page:623-628
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liu Lina¹²³⁴⁵,Yuan Zhenbo¹²³⁴⁵,Pan Rui¹²³⁴⁵,Zeng Yuye¹²³⁴⁵,Lin Aijun¹²³⁴⁵^ORCID,Yao Hequan¹²³⁴⁵^ORCID,Huang Yue⁶⁷³⁴⁵

Affiliation:

1. State Key Laboratory of Natural Medicines (SKLNM) and Department of Medicinal Chemistry

2. School of Pharmacy

3. China Pharmaceutical University

4. Nanjing

5. P. R. China

6. Department of Organic Chemistry

7. School of Science

Abstract

2,3-Dihydrobenzofurans were achieved via a 1,6-conjugated addition-mediated [4 + 1] annulation of ortho-hydroxyphenyl-substituted para-quinone methides in high yields with high diastereoselectivity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C7QO00846E

Reference57 articles.

1. para-Quinone Methide: a New Player in Asymmetric Catalysis

2. Advances in Organocatalytic 1,6-Addition Reactions: Enantioselective Construction of Remote Stereogenic Centers

3. Asymmetric Catalytic 1,6-Conjugate Addition/Aromatization ofpara-Quinone Methides: Enantioselective Introduction of Functionalized Diarylmethine Stereogenic Centers

4. A New Organocatalytic Concept for Asymmetric α-Alkylation of Aldehydes

5. Asymmetric Organocatalytic Synthesis of 3-Diarylmethine-Substituted Oxindoles Bearing a Quaternary Stereocenter via 1,6-Conjugate Addition to para-Quinone Methides

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