Copper(ii) complexes with tridentate halogen-substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving groups and ligand flexibility on antiproliferative activities

Author:

Kordestani Nazanin1234,Amiri Rudbari Hadi1234ORCID,Fernandes Alexandra R.56789ORCID,Raposo Luís R.56789ORCID,Luz André56789,Baptista Pedro V.56789ORCID,Bruno Giuseppe1011121314,Scopelliti Rosario15161718ORCID,Fateminia Zohreh1234,Micale Nicola1011121314ORCID,Tumanov Nikolay119202122ORCID,Wouters Johan119202122ORCID,Abbasi Kajani Abolghasem232425264,Bordbar Abdol-Khalegh123427ORCID

Affiliation:

1. Department of Chemistry

2. University of Isfahan

3. Isfahan 81746-73441

4. Iran

5. UCIBIO

6. Departamento Ciências da Vida

7. Faculdade de Ciências e Tecnologia

8. Universidade NOVA de Lisboa

9. 2829-516 Caparica

10. Department of Chemical

11. Biological

12. Pharmaceutical and Environmental Sciences

13. University of Messina

14. I-98166 Messina

15. Institut des Sciences et Ingénierie Chimiques

16. École Polytechnique Fédérale de Lausanne (EPFL)

17. CH-1015 Lausanne

18. Switzerland

19. Namur Institute of Structured Matter

20. University of Namur

21. 5000 Namur

22. Belgium

23. Applied Physiology Research Center

24. Cardiovascular Research Institute

25. Isfahan University of Medical Sciences

26. Isfahan

27. California Institute for Quantitative Biosciences (QB3)

Abstract

Synthesis and antiproliferative activities of Cu(ii) complexes with tridentate Schiff-base ligands containing pyridine and 3,5-halogen substituted phenol moieties were investigated.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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