Self-assembled DNA nanowires as quantitative dual-drug nanocarriers for antitumor chemophotodynamic combination therapy

Author:

Chen Qiaoshu12345,Li Chunying12345,Yang Xiaohai12345ORCID,Huang Jin12345ORCID,Liu Songyang12345,Liu Wei12345,Liu Jianbo12345ORCID,Wang Kemin12345ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics

2. College of Chemistry and Chemical Engineering

3. Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province

4. Hunan University

5. Changsha 410082

Abstract

Self-assembled DNA nanowires were fabricated through a supersandwich hybridization reaction and co-loaded with a photosensitizer chlorin e6 (Ce6) and a chemotherapeutic drug doxorubicin (DOX) for antitumor chemophotodynamic combination therapy.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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