Brachyantheraoside A8, a new natural nor-oleanane triterpenoid as a kidney-type glutaminase inhibitor fromStauntonia brachyanthera-Reference-Cited by-同舟云学术

Brachyantheraoside A8, a new natural nor-oleanane triterpenoid as a kidney-type glutaminase inhibitor fromStauntonia brachyanthera

Published:2017 Issue:83 Volume:7 Page:52533-52542
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Rong¹²³⁴⁵,Wei Peifeng⁶⁷⁸⁹,Wang Yue¹²³⁴⁵,Liu Ying¹²³⁴⁵,Liu Xuanli¹²³⁴⁵,Meng Dali¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Structure-Based Drug Design and Discovery

2. Ministry of Education

3. School of Traditional Chinese Materia Medica

4. Shenyang Pharmaceutical University

5. Shenyang 110016

6. College of Pharmacy

7. Shaanxi University of Chinese Medicine

8. Xianyang 712000

9. China

Abstract

With the aim of finding a better kidney-type glutaminase (KGA) inhibitor with potential anti-cancer properties, 18 nor-oleanane triterpenoids fromStauntonia brachyanthera, including 2 new ones, were screened against KGA.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA11270J

Reference35 articles.

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