Synthesis, biological evaluation, and molecular docking of novel ferulic acid derivatives containing a 1,3,4-oxadiazole thioether and trifluoromethyl pyrimidine skeleton-Reference-Cited by-同舟云学术

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Synthesis, biological evaluation, and molecular docking of novel ferulic acid derivatives containing a 1,3,4-oxadiazole thioether and trifluoromethyl pyrimidine skeleton

Published:2024 Issue:23 Volume:14 Page:16218-16227
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

An Jiansong¹,Pan Nianjuan¹,Liu Chunyi¹,Chen Haijiang¹,Fei Qiang¹,Gan Xiuhai²^ORCID,Wu Wenneng¹^ORCID

Affiliation:

1. School of Food Science and Engineering, Guiyang University, Guiyang 550005, China

2. National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China

Abstract

Compound 6f displayed better antifungal activity against Phomopsis sp. Our study demonstrated that compound 6f formed hydrogen bonds with SER-17, SER-39, ARG-14 and ARG-43 of SDH.

Funder

Science and Technology Program of Guizhou Province

Guizhou University

Department of Education of Guizhou Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA01765J

Reference39 articles.

1. Azole fungicides - understanding resistance mechanisms in agricultural fungal pathogens

2. Mutations in theCYP51gene reduce DMI sensitivity inParastagonospora nodorumpopulations in Europe and China

3. Design, Synthesis, and Biological Evaluation of Novel Psoralen-Based 1,3,4-Oxadiazoles as Potent Fungicide Candidates Targeting Pyruvate Kinase

4. Potential Risk and Mechanism of Microcystin Induction by Chiral Metalaxyl

5. Natural products that have been used commercially as crop protection agents

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