High affinity interactions of Pb2+ with synaptotagmin I-Reference-Cited by-同舟云学术

High affinity interactions of Pb2+ with synaptotagmin I

Author:

Katti Sachin¹²³⁴,Her Bin¹²³⁴,Srivastava Atul K.¹²³⁴,Taylor Alexander B.⁵⁶⁷⁸⁴,Lockless Steve W.⁹²⁴,Igumenova Tatyana I.¹²³⁴^ORCID

Affiliation:

1. Department of Biochemistry and Biophysics

2. Texas A&M University

3. College Station

4. USA

5. Department of Biochemistry and Structural Biology and the X-ray Crystallography Core Laboratory

6. Institutional Research Cores

7. University of Texas Health Science Center at San Antonio

8. San Antonio

9. Department of Biology

Abstract

Pb²⁺ binds C2 domains with high affinity, desensitizes them to Ca²⁺, and supports their membrane interactions.

Funder

Welch Foundation

National Institute of General Medical Sciences

Division of Chemistry

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

Reference69 articles.

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