A stronger reversal effect of the combination of dasatinib and menadione on P-gp-mediated multidrug resistance in human leukemia K562/Adr cell line
Author:
Affiliation:
1. Department of Clinical Pharmacology
2. College of Pharmacy
3. Dalian Medical University
4. Dalian 116044
5. China
Abstract
Multidrug resistance (MDR) leads to poor efficiency of chemotherapy.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA27999F
Reference32 articles.
1. Modulation of the typical multidrug resistance phenotype by targeting the MED-1 region of human MDR1 promoter
2. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
3. Quantitation of Doxorubicin Uptake, Efflux, and Modulation of Multidrug Resistance (MDR) in MDR Human Cancer Cells
4. The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, andmdr gene expression in colorectal cancer
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