Soft glassy rheology of single cells with pathogenic protein aggregates-Reference-Cited by-同舟云学术

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Soft glassy rheology of single cells with pathogenic protein aggregates

Published:2024 Issue:31 Volume:20 Page:6266-6274
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Rajput Shatruhan Singh¹²^ORCID,Singh Surya Bansi³⁴^ORCID,Subramanyam Deepa³,Patil Shivprasad¹^ORCID

Affiliation:

1. Department of Physics, Indian Institute of Science Education and Research, Pune 411008, India

2. Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK

3. National Centre for Cell Science, SP Pune University Campus, Pune 411007, India

4. SP Pune University, Pune 411007, India

Abstract

Soft glassy rheology of single hemocytes reveals that pathogenic aggregates, restriciting filopodia formation and transport through cytoskeletal remodelling, stiffens the cell with loss of its fluidity.

Funder

Science and Engineering Research Board

National Centre for Cell Science

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SM/D4SM00595C

Reference58 articles.

1. A comparison of methods to assess cell mechanical properties

2. Hallmarks of Life in Single Cell Contact Mechanics: Outstanding Challenges and Perspectives

3. The nanomechanical signature of breast cancer

4. Changes in the stiffness of human mesenchymal stem cells with the progress of cell death as measured by atomic force microscopy

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