Development and validation of an LC-MS/MS method for simultaneous quantification of hesperidin and hesperetin in rat plasma for pharmacokinetic studies-Reference-Cited by-同舟云学术

Development and validation of an LC-MS/MS method for simultaneous quantification of hesperidin and hesperetin in rat plasma for pharmacokinetic studies

Published:2017 Issue:22 Volume:9 Page:3329-3337
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Lee Jr-Ting¹²³⁴,Pao Li-Heng⁵⁶⁷⁸⁴,Hsieh Chang-Da¹²³⁴,Huang Pei-Wei⁹¹⁰¹¹⁴,Hu Oliver Yoa-Pu⁹¹⁰¹¹⁴^ORCID

Affiliation:

1. Department of Pharmacy

2. Taipei Veterans General Hospital Yuli Branch

3. Hualien County 981

4. Republic of China

5. Research Center for Chinese Herbal Medicine and Research Center for Food and Cosmetic Safety

6. College of Human Ecology

7. Chang Gung University of Science and Technology

8. Taoyuan County 333

9. School of Pharmacy

10. National Defense Medical Center

11. Taipei City 114

Abstract

A simple and sensitive method for the determination of hesperidin and hesperetin was necessary for a pharmacokinetic (PK) study in Wistar rats.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/AY/C7AY00051K

Reference39 articles.

1. Flavanone absorption after naringin, hesperidin, and citrus administration*

2. Identification and Quantification of the Conjugated Metabolites Derived from Orally Administered Hesperidin in Rat Plasma

3. Flavonoids can replace α-tocopherol as an antioxidant

4. Chemistry and pharmacology of the citrus bioflavonoid hesperidin

5. Structure-antioxidant activity relationships of flavonoids and phenolic acids

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