Engineering extracellular vesicles derived from macrophages for tumor therapy: a review

Author:

Yan Ying1,Zhang He2,Wei Shiqi234,Xie Weimin1,Chen Ying234,Yang Huaming2134ORCID

Affiliation:

1. Hunan Key Laboratory of Mineral Materials and Application, School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, P. R. China

2. Engineering Research Center of Nano-Geomaterials of Ministry of Education, China University of Geosciences, Wuhan 430074, P. R. China

3. Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, P. R. China

4. Key Laboratory of Functional Geomaterials in China Nonmetallic Minerals Industry, China University of Geosciences, Wuhan 430074, P. R. China

Abstract

Compared to cellular immunotherapy, engineering macrophage-derived EVs which carry nanoparticles, drugs, proteins, nucleic acids etc. can target tumor cells to improve biosafety and treatment efficacy.

Funder

National Key Research and Development Program of China

National Science Fund for Distinguished Young Scholars

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

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