Design, synthesis and biological activity of 4′-[(benzimidazol-1-yl)methyl]biphenyl-2-sulphonamides as dual angiotensin II and endothelin A receptor antagonists-Reference-Cited by-同舟云学术

Design, synthesis and biological activity of 4′-[(benzimidazol-1-yl)methyl]biphenyl-2-sulphonamides as dual angiotensin II and endothelin A receptor antagonists

Published:2015 Issue:4 Volume:6 Page:715-718
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Hao Li-Ping¹²³⁴,Xue Wei-Zhe¹²³⁴,Han Xiao-Feng¹²³⁴,He Xing¹²³⁴,Zhang Jun¹²³⁴,Zhou Zhi-Ming¹²³⁴

Affiliation:

1. R & D Center for Pharmaceuticals

2. Beijing Institute of Technology

3. Beijing

4. PR China

Abstract

A series of novel 4′-[(benzimidazol-1-yl)methyl]biphenyl-2-sulphonamides was designed, and their molecular model simulation fitting to a new HipHop 3D pharmacophore model was examined.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C4MD00499J

Reference25 articles.

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2. Angiotensin Receptors and Their Antagonists

3. Tolerability and treatment compliance with angiotensin II receptor antagonists

4. Endothelin Receptor Antagonists

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