Chorismatases – the family is growing
Author:
Affiliation:
1. Institute of Pharmaceutical Sciences
2. University of Freiburg
3. 79104 Freiburg
4. Germany
5. Institute of Biochemistry and Technical Biochemistry
6. University of Stuttgart
7. 70569 Stuttgart
Abstract
A newly discovered subfamily of chorismatases catalyses the same reaction as chorismate lyases (cleavage of chorismate to 4-hydroxybenzoate), but does not suffer from product inhibition.
Funder
Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg
Deutsche Forschungsgemeinschaft
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB03038C
Reference37 articles.
1. A Metabolic Node in Action: Chorismate-Utilizing Enzymes in Microorganisms
2. The Shikimate Pathway and Aromatic Amino Acid Biosynthesis in Plants
3. Unraveling the Structure and Mechanism of the MST(ery) Enzymes
4. From scratch to value: engineering Escherichia coli wild type cells to the production of l-phenylalanine and other fine chemicals derived from chorismate
5. Diversity-Oriented Production of Metabolites Derived from Chorismate and Their Use in Organic Synthesis
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