Recent advances in the asymmetric synthesis of pharmacology-relevant nitrogen heterocycles via stereoselective aza-Michael reactions-Reference-Cited by-同舟云学术

Recent advances in the asymmetric synthesis of pharmacology-relevant nitrogen heterocycles via stereoselective aza-Michael reactions

Published:2019 Issue:15 Volume:17 Page:3670-3708
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Vinogradov Maxim G.¹²³⁴^ORCID,Turova Olga V.¹²³⁴^ORCID,Zlotin Sergei G.¹²³⁴^ORCID

Affiliation:

1. N.D. Zelinsky Institute of Organic Chemistry

2. Russian Academy of Sciences

3. 119991 Moscow

4. Russian Federation

Abstract

In this review, recent applications of a stereoselective aza-Michael reaction for asymmetric synthesis of naturally occurring N-containing heterocyclic scaffolds and their usefulness to pharmacology are summarized.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB03034K

Reference270 articles.

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3. Organocatalytic Michael and Friedel–Crafts reactions in enantioselective synthesis of biologically active compounds

4. Stereoselective reactions of nitro compounds in the synthesis of natural compound analogs and active pharmaceutical ingredients

5. Asymmetric catalyzed intramolecular aza-Michael reaction mediated by quinine-derived primary amines

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