Aminophosphonates and aminophosphonic acids with tetrasubstituted stereogenic center: diastereoselective synthesis from cyclic ketimines

Author:

Iwanejko Jakub12345ORCID,Brol Anna12345ORCID,Szyja Bartłomiej M.62375ORCID,Daszkiewicz Marek89105ORCID,Wojaczyńska Elżbieta12345ORCID,Olszewski Tomasz K.12345ORCID

Affiliation:

1. Department of Organic Chemistry

2. Faculty of Chemistry

3. Wrocław University of Science and Technology

4. 50-370 Wrocław

5. Poland

6. Division of Fuels Chemistry and Technology

7. 50-344 Wrocław

8. Institute of Low Temperature and Structure Research

9. Polish Academy of Sciences

10. 50-422 Wrocław

Abstract

Chiral tetrasubstituted aminophosphonic acid derivatives of hexahydroquinoxalin-2(1H)-one were synthesised via diastereoselective hydrophosphonylation of corresponding imines with tris(trimethylsilyl)phosphite as phosphorus nucleophile.

Funder

Ministerstwo Nauki i Szkolnictwa Wyższego

Polska Akademia Nauk

Infrastruktura PL-Grid

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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