Thermoresponsive properties of polyacrylamides in physiological solutions-Reference-Cited by-同舟云学术

Thermoresponsive properties of polyacrylamides in physiological solutions

Published:2021 Issue:35 Volume:12 Page:5077-5084
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Kolouchová Kristýna¹^ORCID,Lobaz Volodymyr¹^ORCID,Beneš Hynek¹,de la Rosa Victor R.²³^ORCID,Babuka David¹⁴,Švec Pavel¹⁵^ORCID,Černoch Peter¹^ORCID,Hrubý Martin¹^ORCID,Hoogenboom Richard²^ORCID,Štěpánek Petr¹^ORCID,Groborz Ondřej¹⁶⁷^ORCID

Affiliation:

1. Institute of Macromolecular Chemistry, Czech Academy of Science, Heyrovsky square 2, 162 06 Prague 6, Czech Republic

2. Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Ghent, Belgium

3. AVROXA BV, Technologiepark-Zwijnaarde 82, B-9052 Ghent, Belgium

4. Department of Biophysics, Institute of Physics, Faculty of Mathematics and Physics, Charles University, Ke Karlovu 3, Prague 2, 121 16, Czech Republic

5. Department of Physical and Macromolecular Chemistry, Faculty of Sciences, Charles University, Hlavova 8, Prague 2, 128 00, Czech Republic

6. Institute of Biophysics and Informatics, Charles University, First Faculty of Medicine, Salmovská 1, 120 00 Prague 2, Czech Republic

7. Department of Organic and Medicinal Chemistry, Charles University, Faculty of Science, Hlavova 8, 128 43 Prague 2, Czech Republic

Abstract

We show that the cloud point temperature (TCP) of thermoresponsive polyacrylamides is considerably lower in physiologically relevant solvents (phosphate-buffered saline, serum) than in pure water. This decrease of TCP may be critical for some biomedical applications.

Funder

Grantová Agentura, Univerzita Karlova

Grantová Agentura České Republiky

Technology Agency of the Czech Republic

Fonds Wetenschappelijk Onderzoek

Universiteit Gent

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/PY/D1PY00843A