Synthesis and biological evaluation of S-lipidated lipopeptides of a connexin 43 channel inhibitory peptide-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of S-lipidated lipopeptides of a connexin 43 channel inhibitory peptide

Author:

Yang Sung-Hyun¹²³⁴⁵,Clemett Connor A.⁶⁷⁸⁹³,Brimble Margaret A.¹²³⁴⁵^ORCID,O'Carroll Simon J.⁶⁷⁸⁹³,Harris Paul W. R.¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemical Sciences

2. The University of Auckland

3. Auckland

4. New Zealand

5. School of Biological Sciences

6. Department of Anatomy Medical Imaging

7. School of Medical Sciences

8. Faculty of Medical and Health Sciences, and Centre for Brain Research

9. University of Auckland

Abstract

Lipidated Peptide5 analogues are able to mediate hemichannel openings leading to inhibition of chemical messengers to the extracellular matrix.

Funder

Auckland Medical Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

Reference53 articles.

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