Titanium dioxide nanoparticles enhance macrophage activation by LPS through a TLR4-dependent intracellular pathway-Reference-Cited by-同舟云学术

Titanium dioxide nanoparticles enhance macrophage activation by LPS through a TLR4-dependent intracellular pathway

Published:2015 Issue:2 Volume:4 Page:385-398
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Bianchi Massimiliano G.¹²³⁴⁵,Allegri Manfredi⁶⁷⁸³⁹,Costa Anna L.¹⁰¹¹¹²⁵,Blosi Magda¹⁰¹¹¹²⁵,Gardini Davide¹⁰¹¹¹²⁵,Del Pivo Camilla¹⁰¹¹¹²⁵,Prina-Mello Adriele¹³¹⁴¹⁵¹⁶,Di Cristo Luisana¹²³⁴⁵,Bussolati Ovidio⁶⁷⁸³⁹,Bergamaschi Enrico¹²³⁴⁵

Affiliation:

1. Unit of Occupational Medicine

2. Department of Clinical and Experimental Medicine

3. University of Parma

4. 43026 Parma

5. Italy

6. Unit of General Pathology

7. Department of Biomedical

8. Biotechnological and Translational Sciences

9. 43025 Parma

10. Institute of Science and Technology for Ceramics (CNR-ISTEC)

11. National Research Council of Italy

12. 48018 Faenza (RA)

13. Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN) and School of Medicine

14. Trinity College Dublin

15. Dublin

16. Ireland

Abstract

TiO₂nanoparticles enhance LPS-dependent NO production and cytokine secretion through a mechanism that involves TLR4-mediated p38-signalling and requires phagocytosis.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TX/C4TX00193A

Reference59 articles.

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4. Titanium dioxide nanoparticles: a review of current toxicological data

5. Inhalation Exposure Study of Titanium Dioxide Nanoparticles with a Primary Particle Size of 2 to 5 nm

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