ABC triblock bottlebrush copolymer-based injectable hydrogels: design, synthesis, and application to expanding the therapeutic index of cancer immunochemotherapy-Reference-Cited by-同舟云学术

ABC triblock bottlebrush copolymer-based injectable hydrogels: design, synthesis, and application to expanding the therapeutic index of cancer immunochemotherapy

Published:2020 Issue:23 Volume:11 Page:5974-5986
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Vohidov Farrukh¹²³,Milling Lauren E.⁴²⁵³,Chen Qixian¹²³^ORCID,Zhang Wenxu¹²³,Bhagchandani Sachin¹²³,Nguyen Hung V.-T.¹²³,Irvine Darrell J.⁴²⁵³^ORCID,Johnson Jeremiah A.¹²³⁴²^ORCID

Affiliation:

1. Department of Chemistry

2. Massachusetts Institute of Technology

3. USA

4. Koch Institute for Integrative Cancer Research

5. Cambridge

Abstract

Triblock bottlebrush copolymers with an "ABC" sidechain sequence form thermally reversible hydrogels for sustained delivery of paclitaxel and resiquimod, improving the efficacy and safety of this potent cancer immunochemotherapy.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC02611E

Reference81 articles.

1. Solvent-free, supersoft and superelastic bottlebrush melts and networks

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3. Precisely Tunable Photonic Crystals From Rapidly Self-Assembling Brush Block Copolymer Blends