3D printing of a tough double-network hydrogel and its use as a scaffold to construct a tissue-like hydrogel composite

Author:

Du Cong1ORCID,Hu Jian2ORCID,Wu Xinyu1,Shi Huimin3,Yu Hai Chao1,Qian Jin4,Yin Jun3ORCID,Gao Changyou1ORCID,Wu Zi Liang1ORCID,Zheng Qiang1

Affiliation:

1. Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China

2. State Key Laboratory for Strength and Vibration of Mechanical Structures, International Center for Applied Mechanics, Department of Engineering Mechanics, Xi’an Jiaotong University, Xi’an 710049, China

3. State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University, Hangzhou 310028, China

4. Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province, Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, China

Abstract

3D printed tough hydrogel constructs with high fidelity and stability are prepared by extrusion-based printing and further used as scaffolds filled with a cell-laden soft gel to develop a tissue-like hydrogel composite.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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