Copper-mediated C(sp3)–H amination in a multiple C–N bond-forming strategy for the synthesis of N-heterocycles

Author:

Xie Zeqiang12345,Peng Jiangling12345,Zhu Qiang12345

Affiliation:

1. State Key Laboratory of Respiratory Disease

2. Guangzhou Institutes of Biomedicine and Health

3. Chinese Academy of Sciences

4. Guangzhou 510530

5. China

Abstract

A three-component reaction for the construction of imidazo[1,5-a]pyridines through copper-promoted C(sp3)–H amination has been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference87 articles.

1. Making carbon-nitrogen bonds in biological and chemical synthesis

2. Amino Group Chemistry: From Synthesis to the Life Sciences, ed. A. Ricci, Wiley-VCH, Weinheim, Germany, 2007

3. Structural and Molecular Recognition Studies with Acyclic Anion Receptors

4. Metal-Catalyzed Cross-Coupling Reactions, ed. A. Meijere and F. Diederich, Wiley-VCH, Weinheim, 2004

5. Modern Synthetic Methods for Copper-Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation

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