Excited state proton transfer in the triplet state of 8-hydroxy-5-nitroquinoline: a transient absorption and time-resolved resonance Raman spectroscopic study-Reference-Cited by-同舟云学术

Excited state proton transfer in the triplet state of 8-hydroxy-5-nitroquinoline: a transient absorption and time-resolved resonance Raman spectroscopic study

Published:2023 Issue:1 Volume:25 Page:402-409
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Wang Ran¹,Zhang Fengjin¹,Pan Xinghang¹,Zheng Xuming¹,Xue Jiadan¹²^ORCID,Du Yong³^ORCID,Xie Binbin⁴^ORCID

Affiliation:

1. Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou, 310018, China

2. Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, 310018, China

3. Center for THz Research, China Jiliang University, Hangzhou, 310018, China

4. Zhejiang Normal University, Hangzhou Institute of Advanced Studies, Hangzhou 310018, China

Abstract

8-Hydroxy-5-nitroquinoline is an antimicrobial, anti-inflammatory and anticancer agent. Our findings on its photochemistry reveal that it tautomerizes and dissociates in the excited state, suggesting the drug delivered should be protected from light.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CP/D2CP04315G

Reference57 articles.

1. Transcript Profiling of Nitroxoline-Treated Biofilms Shows Rapid Up-regulation of Iron Acquisition Gene Clusters

2. Effect of 8-hydroxyquinoline and derivatives on human neuroblastoma SH-SY5Y cells under high glucose