Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer-Reference-Cited by-同舟云学术

Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer

Published:2020 Issue:17 Volume:8 Page:3789-3800
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Chen Shih-Hong¹²³⁴⁵,Liu Te-I¹²³⁴^ORCID,Chuang Cheng-Lin¹²³⁴,Chen Hsin-Hung⁶⁷⁸⁴,Chiang Wen-Hsuan⁶⁷⁸⁴^ORCID,Chiu Hsin-Cheng¹²³⁴^ORCID

Affiliation:

1. Department of Biomedical Engineering and Environmental Sciences

2. National Tsing Hua University

3. Hsinchu 30013

4. Taiwan

5. Department of Anesthesiology

6. Department of Chemical Engineering

7. National Chung Hsing University

8. Taichung 402

Abstract

Through hierarchically targeting bone matrix and tumor cells, PTX-carrying ALN/FA-nanoparticles substantially accumulate in bone metastases and improve mice survival rate.

Funder

National Tsing Hua University

Ministry of Science and Technology, Taiwan

National Taiwan University Hospital

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/D0TB00046A

Reference35 articles.

1. The role of extracellular calcium in bone metastasis

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4. Poly(ethylene glycol)–paclitaxel–alendronate self-assembled micelles for the targeted treatment of breast cancer bone metastases

5. Bisphosphonate-functionalized coordination polymer nanoparticles for the treatment of bone metastatic breast cancer

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