Scar prevention through topical delivery of gelatin-tyramine-siSPARC nanoplex loaded in dissolvable hyaluronic acid microneedle patch across skin barrier-Reference-Cited by-同舟云学术

Scar prevention through topical delivery of gelatin-tyramine-siSPARC nanoplex loaded in dissolvable hyaluronic acid microneedle patch across skin barrier

Published:2022 Issue:14 Volume:10 Page:3963-3971
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Chun Yong Yao¹,Tan William Wei Ren²^ORCID,Vos Marcus Ivan Gerard²,Chan Wen Kiat¹,Tey Hong Liang²³⁴^ORCID,Tan Nguan Soon²⁵^ORCID,Tan Timothy Thatt Yang¹^ORCID

Affiliation:

1. School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Dr, Singapore 637459

2. Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, Singapore 308232

3. National Skin Centre, 1 Mandalay Road, Singapore 308205

4. Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228

5. School of Biological Sciences, Nanyang Technological University, 60 Nanyang Dr, Singapore 637551

Abstract

Dissolvable microneedle patch made of HA designed for delivery of siSPARC across skin barrier to prevent scar formation.

Funder

Ministry of Education - Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00572G

Reference42 articles.

1. The Treatment of keloids and hypertrophic scars with intralesional bleomycin in skin of color

2. What is the prevalence of hypertrophic scarring following burns?

3. Immunology of Wound Healing

4. The role of macrophages in the formation of hypertrophic scars and keloids

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