The molecular mechanism of robust macrophage immune responses induced by PEGylated molybdenum disulfide-Reference-Cited by-同舟云学术

The molecular mechanism of robust macrophage immune responses induced by PEGylated molybdenum disulfide

Published:2019 Issue:46 Volume:11 Page:22293-22304
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Gu Zonglin¹²³⁴⁵,Chen Serena H.⁶⁷⁸⁹^ORCID,Ding Zhaowen¹⁰¹¹¹²¹³¹⁴,Song Wei¹²³⁴⁵,Wei Wei¹⁰¹¹¹²¹³¹⁴^ORCID,Liu Shengtang¹⁵¹⁶¹⁷¹⁸¹⁹,Ma Guanghui¹⁰¹¹¹²¹³¹⁴^ORCID,Zhou Ruhong¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Quantitative Biology

2. Department of Physics

3. Zhejiang University

4. Hangzhou 310027

5. China

6. Computational Biology Center

7. IBM Thomas J. Watson Research Center

8. Yorktown Heights

9. USA

10. State Key Laboratory of Biochemical Engineering

11. Institute of Process Engineering

12. Chinese Academy of Sciences

13. Beijing 100190

14. PR China

15. State Key Laboratory of Radiation Medicine and Protection

16. School of Radiation Medicine and Protection

17. Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions

18. Soochow University

19. Jiangsu 215123

Abstract

Molecular dynamics simulation and experiments reveal that PEGylated MoS₂ triggers more sustained stimulation to macrophage than pristine MoS₂via slower/prolonged membrane penetration and stronger membrane adsorption.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NR/C9NR04358F

Reference71 articles.

1. Dissociation of H2O at the vacancies of single-layer MoS2

2. Hysteresis in Single-Layer MoS2 Field Effect Transistors