Investigation of novel Mn(<scp>ii</scp>) fenamato complexes with neocuproine and their effects on endometrial cell lines-Reference-Cited by-同舟云学术

Investigation of novel Mn(ii) fenamato complexes with neocuproine and their effects on endometrial cell lines

Published:2023 Issue:28 Volume:47 Page:13088-13097
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Klepcová Zuzana¹,Špaková Ivana¹,Madreiter-Sokolowski Corina T.²,Graier Wolfgang²,Kalinová Katarína¹,Samoľová Erika³^ORCID,Smolková Romana⁴^ORCID,Smolko Lukáš¹^ORCID,Rabajdová Miroslava¹

Affiliation:

1. Department of Medical and Clinical Biochemistry, P. J. Šafárik University in Košice, Trieda SNP 1, SK-04011, Košice, Slovakia

2. Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging Molecular Biology and Biochemistry, Medical University of Graz, Neue Stiftingtalstrasse 6/4 OST, AT-8010, Graz, Austria

3. Institute of Physics of the Czech Academy of Sciences, Cukrovarnicka 10, CZ-18221, Praha, Czechia

4. Department of Ecology, Faculty of Humanities and Natural Sciences, University of Prešov, Ul. 17. novembra, SK-08001, Prešov, Slovakia

Abstract

Two isostructural complexes [Mn(neo)(fen)2] (1) and [Mn(neo)(flu)2] (2) show different biological activity on endometrial cell lines. Flufenamato complex effectively triggers apoptosis mediated by caspase activation in endometriotic 12Z cell line.

Funder

European Regional Development Fund

Slovak Academic Information Agency

Austrian Science Fund

Vedecká Grantová Agentúra MŠVVaŠ SR a SAV

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ00412K

Reference58 articles.

1. Endometriosis, WHO, https://www.who.int/news-room/fact-sheets/detail/endometriosis (accessed December 2022)

2. Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

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