14N–1H HMQC solid-state NMR as a powerful tool to study amorphous formulations – an exemplary study of paclitaxel loaded polymer micelles-Reference-Cited by-同舟云学术

14N–1H HMQC solid-state NMR as a powerful tool to study amorphous formulations – an exemplary study of paclitaxel loaded polymer micelles

Published:2020 Issue:31 Volume:8 Page:6827-6836
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Grüne Marvin¹²³⁴,Luxenhofer Robert⁵²⁶⁴^ORCID,Iuga Dinu⁷⁸⁹¹⁰,Brown Steven P.⁷⁸⁹¹⁰^ORCID,Pöppler Ann-Christin¹²³⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry

2. University of Würzburg

3. 97074 Würzburg

4. Germany

5. Lehrstuhl für Chemische Technologie der Materialsynthese

6. 97070 Würzburg

7. Department of Physics

8. University of Warwick

9. Coventry

10. UK

Abstract

¹⁴N–¹H HMQC experiments are powerful experiments to characterize amorphous drug–polymer formulations of paclitaxel yielding well-separated signals in the ¹⁴N dimension as well as information on the symmetry of ¹⁴N and ¹⁴N–¹H interactions.

Funder

Royal Society

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

Advantage West Midlands

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/D0TB00614A