Determination of atomoxetine levels in human plasma using LC-MS/MS and clinical application to Chinese children with ADHD based on CPIC guidelines

Author:

Xia Ying12345ORCID,Guo Hong-Li12345ORCID,Hu Ya-Hui12345ORCID,Long Jia-Yi12345,Chen Jing6345,Chen Feng12345ORCID,Ji Xing12345ORCID

Affiliation:

1. Pharmaceutical Sciences Research Center

2. Department of Pharmacy

3. Children's Hospital of Nanjing Medical University

4. Nanjing 210008

5. China

6. Department of Neurology

Abstract

This paper focuses on the determination of atomoxetine in human plasma. The work can provide therapeutic recommendations regarding atomoxetine and help clinicians in dose optimization.

Funder

Jiangsu Provincial Commission of Health and Family Planning

Nanjing Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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