Metal complexes of pyridine-fused macrocyclic polyamines targeting the chemokine receptor CXCR4-Reference-Cited by-同舟云学术

Metal complexes of pyridine-fused macrocyclic polyamines targeting the chemokine receptor CXCR4

Published:2015 Issue:42 Volume:13 Page:10517-10526
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hamal Sunil¹²³⁴,D'huys Thomas⁵⁶⁷⁸⁹,Rowley William F.¹²³⁴,Vermeire Kurt⁵⁶⁷⁸⁹,Aquaro Stefano¹⁰¹¹¹²¹³,Frost Brian J.¹²³⁴,Schols Dominique⁵⁶⁷⁸⁹,Bell Thomas W.¹²³⁴

Affiliation:

1. Department of Chemistry

2. University of Nevada

3. Reno

4. USA

5. Department of Microbiology and Immunology

6. Rega Institute for Medical Research

7. University of Leuven

8. Leuven

9. Belgium

10. Department of Experimental Medicine and Biochemical Sciences

11. University of Rome Tor Vergata

12. Rome

13. Italy

Abstract

Newly synthesized pyridopentaazacyclopentadecanes and their transition metal complexes are shown to interact with the human chemokine receptor CXCR4, a key target for developing new therapeutic agents.

Funder

Division of Chemistry

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01557J

Reference47 articles.

1. CXCR4 Chemokine Receptor Overview: Biology, Pathology and Applications in Imaging and Therapy

2. Small Molecule Inhibitors of CXCR4

3. K. S. Kazmierski , Wielslaw M.Gudmundsson and S. C.Piscitelli, in Annual Reports in Medicinal Chemistry, ed. J. E. Macor, Elsevier, 2007, pp. 301–320

4. Antiretroviral Treatment of Adult HIV Infection

5. CXCL12–CXCR4 contributes to the implication of bone marrow in cancer metastasis

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeting emerging cancer hallmarks by transition metal complexes: Cancer stem cells and tumor microbiome. Part I;Coordination Chemistry Reviews;2023-02

2. Triple M as Manganese: Medicine, magnetism and macrocycles. Seven-coordinate Mn(II) complexes with pyridine-based macrocyclic ligands;Polyhedron;2021-07

3. Aromatic and heteroaromatic azacrown compounds: advantages and disadvantages of rigid macrocyclic ligands;Russian Chemical Reviews;2020-07-01

4. Supermolecules as Medicinal Drugs;Handbook of Macrocyclic Supramolecular Assembly;2020

5. BIOMIMETIC APPROACHES TO STUDY OF PROPERTIES OF MEDICINAL SUBSTANCES;IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA;2019-10-29