Protein corona formation moderates the release kinetics of ion channel antagonists from transferrin-functionalized polymeric nanoparticles-Reference-Cited by-同舟云学术

Protein corona formation moderates the release kinetics of ion channel antagonists from transferrin-functionalized polymeric nanoparticles

Published:2020 Issue:5 Volume:10 Page:2856-2869
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Naidu Priya S. R.¹²³⁴^ORCID,Denham Eleanor⁵⁶⁷⁴,Bartlett Carole A.⁵⁶⁷⁴,McGonigle Terry⁵⁶⁷⁴,Taylor Nicolas L.¹²³⁴⁸^ORCID,Norret Marck¹²³⁴,Smith Nicole. M.¹²³⁴^ORCID,Dunlop Sarah A.⁹²³⁴^ORCID,Iyer K. Swaminathan¹²³⁴^ORCID,Fitzgerald Melinda⁵⁶⁷⁴⁹^ORCID

Affiliation:

1. School of Molecular Sciences

2. The University of Western Australia

3. Crawley

4. Australia

5. Curtin Health Innovation Research Institute

6. Curtin University

7. Bentley

8. Australian Research Council Centre of Excellence in Plant Energy Biology

9. School of Biological Sciences

Abstract

Transferrin (Tf)-functionalized p(HEMA-ran-GMA) nanoparticles were designed to incorporate and release a water-soluble combination of three ion channel antagonists, identified as a promising therapy for secondary degeneration following neurotrauma.

Funder

National Health and Medical Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA09523C

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