High-throughput mapping of brain-wide activity in awake and drug-responsive vertebrates-Reference-Cited by-同舟云学术

High-throughput mapping of brain-wide activity in awake and drug-responsive vertebrates

Published:2015 Issue:3 Volume:15 Page:680-689
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Lin Xudong¹²³⁴,Wang Shiqi¹²³⁴,Yu Xudong¹²³⁴,Liu Zhuguo⁵⁶⁷,Wang Fei⁵⁶⁷,Li Wai Tsun⁸²³⁴,Cheng Shuk Han⁸²³⁴,Dai Qiuyun⁸²³⁴,Shi Peng¹²³⁴⁹

Affiliation:

1. Department of Mechanical and Biomedical Engineering

2. City University of Hong Kong

3. Kowloon

4. China 999077

5. Beijing Institute of Biotechnology

6. Beijing

7. China 100071

8. Department of Biomedical Science

9. Shenzhen Research Institute

Abstract

A microfluidic system, Fish-Trap, was developed to enable automatic, gel-free, and anesthetic-free immobilization and orientation of zebrafish larvae, allowing high-throughput mapping of drug-induced brain-wide neural activity in awake vertebrates with single-cell resolution.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/LC/C4LC01186D

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